See Negrino Index and pp.

61 - New Document page defaults
76 - Primary & Secondary Browsers
136 - CSS Preferences
233 - Accessibility Category
420 - File Types/Editors
459 - Code Format Settings
484 - Code Rewriting

Prof. Kimball's How to Build A Web Site. Modifying Text, Chapter 3.

Chapter 3 - Pages 57 - 84

First, build a simple web page without using one of Dreamweaver's Sample pages.  You need to learn Type Sizes, Ems, and Cascading Style Sheets before using the sample pages.  Learn the basics first; then you'll better understand the possibilities and options contained in the Sample Pages:

Oh, so you really want to know the right sample format to choose, right?

OK, OK....

For Level 1 (home, index page) and Level 2 (Big Topics) pages, choose:

File > New > Blank Page > HTML >
3 Column hybrid, Header and Footer

2nd Alternate for Level 3 Pages:

File > New > Blank Page > HTML >
2 Column hybrid, Left Sidebar, Header and Footer

What's an Em?
Ems for font size - About.com article
Ems for page size -
Create a page with CSS Layout: 

  Help > Dreamweaver Help > Creating Pages with CSS > Laying Out Pages with CSS > Create A Page with a CSS Layout

Chapter 5 - pp. 133 - 160, "Styling Page Content:"  External Style Sheets - pp. 162 - 167
Cascading Style Sheets

Montgomery College's leveltwo.css styles

CSS Tutorials - About.com

1. Tag Style - p.138  p {font: "Comic Sans MS" ; }
2. Custom Class - p. 143  .red { color: #FF0000 ; }
3. ID Classes p. 144 = Divisions 
   1. <div id="maincontent"> Welcome!   </div>
   2. #maincontent { margin: 5px; }
4. Advanced Styles / Pseudoclasses (divisions, links) p. 145
   1. #maincontent a:visited { color: #69330F; text-decoration: underline; }